ScienceDaily (2010-05-31) -- University of Alberta researchers have identified one of the body's natural self-repair mechanisms that kick in after spinal cord(脊髓) injury which could lead to the development of more effective treatments.
To help understand the discovery the researchers say it is important to first describe the neurons in the spinal cord that control muscle contractions. These neurons represent a fairly autonomous part of the nervous system that control many basic functions such as walking and bladder control. These neurons are brought into a state of readiness by a transmitter called serotonin. Serotonin originates in the brain and projects down the spinal cord where it binds to serotonin receptors on the neurons. This process turns a quiet neuron into one that's ready to respond to fast inputs from the brain.
University of Alberta's Faculty of Rehabilitation Medicine 復建醫學系？(病殘人的)康復
Katherine C Murray, Aya Nakae, Marilee J Stephens, Michelle Rank, Jessica D'Amico, Philip J Harvey, Xiaole Li, R Luke W Harris, Edward W Ballou, Roberta Anelli, Charles J Heckman, Takashi Mashimo, Romana Vavrek, Leo Sanelli, Monica A Gorassini, David J Bennett, Karim Fouad. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nature Medicine, 2010; DOI: 10.1038/nm.2160