about this blog

this is merely to denote myself about my body.

mainly on the record of some morphological, anatomial, and medical aspects.
[since 2010.05.24]
主要是記述在我學我的身體時得到的一些拉七拉雜的資料,不過我想可能不是對我自己有用而已,所以有一些我會多多少少地改成中文化。all the news may be the important informations so i would translate to short notes here. [2010.05.29]

Tuesday, June 22, 2010

Making enough red blood cells: Scientists identify molecules that ensure red blood cell production

ScienceDaily (2010-06-06) -- Scientists have identified two small RNA molecules which ensure that enough red blood cells are produced efficiently, by fine-tuning a number of different genes involved in this process.


To form red blood cells, large, round cells known as precursors have to become small and disc-shaped, like balls of plasticine squeezed between finger and thumb. In the process, they must also produce the large quantities of haemoglobin that will allow them to transport oxygen, and shrink and dispose of their nucleus. The EMBL scientists found that two microRNAs, called MiR144 and MiR451, control the final stages of this process.

blood cell formation, or haematopoiesis

Journal Reference:
K. D. Rasmussen, S. Simmini, C. Abreu-Goodger, N. Bartonicek, M. Di Giacomo, D. Bilbao-Cortes, R. Horos, M. Von Lindern, A. J. Enright, D. O'Carroll. The miR-144/451 locus is required for erythroid homeostasis. Journal of Experimental Medicine, 2010; DOI: 10.1084/jem.20100458

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