ScienceDaily (2010-05-27) -- Researchers have discovered a new interaction between a cell signaling system and a specific gene that may be the cause of B-cell lymphoma. The finding suggests a similar interaction could be occurring during the development of other types of cancer, leading to further understanding of how cancer works -- and how it might be stopped.
佛羅里達大學藥學院,Kato, 發現 BCL6(基因),會產生B-cell lymphomas,在胚胎發育早期,可以抑制細胞間傳遞的通路 (Notch signaling),導致先天疾病。
the Notch signaling pathway, which creates the equivalent of a molecular highway across a cell's membrane, is involved in many types of cell-to-cell interaction, including neuron development, stem cell differentiation and apoptosis (programmed cell death).
Notch signaling pathway在細胞間,產生相等的分子高速公路,且涉及了細胞間的交互作用,包括了...
藉由研究BCL6及Notch signaling可以多方瞭解癌症生成的原因。
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