about this blog

this is merely to denote myself about my body.

mainly on the record of some morphological, anatomial, and medical aspects.
[since 2010.05.24]
主要是記述在我學我的身體時得到的一些拉七拉雜的資料,不過我想可能不是對我自己有用而已,所以有一些我會多多少少地改成中文化。all the news may be the important informations so i would translate to short notes here. [2010.05.29]

Thursday, August 2, 2012

Peptide Controls Blood Sugar in People With Congenital Hyperinsulinism, Pilot Study Suggests

ScienceDaily (Aug. 1, 2012) — A pilot study in adolescents and adults has found that an investigational drug shows promise as the first potential medical treatment for children with the severest type of congenital hyperinsulinism, a rare but potentially devastating disease in which gene mutations cause insulin levels to become dangerously high.

congenital hyperinsulinism

  • There is currently no effective medicine for children with the most common and most severe form of hyperinsulinism, 
  • this investigational drug, a peptide called exendin-(9-39), controls blood sugar levels in people, a very promising result. 

Journal Reference:
  1. Diva D. De Leon. The GLP-1 Receptor Antagonist Exendin-(9-39) Elevates Blood Fasting Glucose Levels in Congenital Hyperinsulinism due to Inactivating Mutations in the ATP-sensitive Potassium Channel.Diabetes, October 2012 DOI: 10.2337/db12-0166

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