Genes tied to deadliest ovarian cancers identified

ScienceDaily (2010-09-08) -- Scientists have identified two genes whose mutations appear to be linked to ovarian clear cell carcinoma, one of the most aggressive forms of ovarian cancer. Clear cell carcinoma is generally resistant to standard therapy.

carcinoma:

1. A cancer arising in the epithelial tissue of the skin or of the lining of the internal organs

2. (wikipedia)

sarcoma 【醫】肉腫,肉瘤

1. A malignant tumor of connective or other nonepithelial tissue

2. (wikipedia)

Sian Jones, Tian-Li Wang, Ie-Ming Shih, Tsui-Lien Mao, Kentaro Nakayama, Richard Roden, Ruth Glas, Dennis Slamon, Luis A. Diaz Jr., Bert Vogelstein, Kenneth W. Kinzler, Victor E. Velculescu, and Nickolas Papadopoulos.Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma. Science, 2010; DOI: 10.1126/science.1196333