單寧酸可能會使白斑症惡化

[2010.12.12] 轉貼自我的文件裡，一年多了，都還沒處理。
就放這裡了~~有空再說。


更新日期:2009/11/09 00:07 【台北訊】 台灣新生報

一名女大學生趕搭油切茶瘦身熱潮，天天喝四瓶以上超濃度茶品，不久後手腳顏面出現圓形、橢圓形的白斑。她經醫師診斷才知道，含單寧酸的濃茶可能會使白斑症惡化。

診治女大學生的開業中醫師袁國山昨天表示，台灣約有二十三萬至四十六萬人有白斑症困擾，大多數病情緩慢進展，很少急速惡化。這名女大學生忽略茶單寧為誘發白斑症的危險因子而暴飲濃茶，導致惡化。經停止茶飲並配合治療後，已控制病情。

袁國山解釋，白斑症是一種全身性與免疫系統相關的疾病。濃茶中的單寧酸屬多酚類物質，對體質特殊的患者而言，短時間大量攝取單寧酸，會引起人體細胞的某些免疫反應，可能造成白斑惡化或復發。

袁國山提醒，除需小心濃茶的單寧酸，白斑症患者應注意其它的飲食刺激，例如柑橘類水果，檸檬、金桔、柳橙、橘子、葡萄柚、柚子等富含維生素C的蔬果，短期大量暴食，也易使病情產生惡化。

袁國山建議，白斑症患者可多攝取含銅、鋅、鐵、鈣等礦物質及B群維生素的食物，如黑豆、牛奶、黑芝麻等。白斑症的中醫藥方與食補，以當歸、川芎、白杓、熟地、漢蓮草、黃耆、紅景天及女貞子等活血理氣藥方，較為有效。

Bone marrow plays critical role in enhancing immune response to viruses, researchers find

ScienceDaily (2010-06-01) -- Researchers for the first time have determined that bone marrow cells play a critical role in fighting respiratory viruses, making the bone marrow a potential therapeutic target, especially in people with compromised immune systems. They have found that during infections of the respiratory tract, cells produced by the bone marrow are instructed by proteins to migrate to the lungs to help fight infection.

科學家首次發現髓細胞扮演人體抵抗病體的主要功能.

Bone marrow is the soft fatty substance inside human or animal bones.


Journal Reference:
Tamar Hermesh, Bruno Moltedo, Thomas M. Moran, Carolina B. López. Antiviral Instruction of Bone Marrow Leukocytes during Respiratory Viral Infections. Cell Host & Microbe, 2010; 7 (5): 343-353 DOI: 10.1016/j.chom.2010.04.006

Inflammasome increases muscle damage in muscular dystrophy, study finds

ScienceDaily (2010-06-01) -- In a new study, researchers demonstrate that affected muscle may directly contribute to inflammation in muscular dystrophy.

發炎直接導致肌肉萎縮

To investigate the role of the inflammasome, which is responsible for activation of inflammatory processes, in muscular dystrophy, Rawat et al examined the inflammasome platform in mouse and human tissues that develop limb girdle muscular dystrophy type 2B (LGMD2B). They found that components of the inflammasome pathway were upregulated and activated in diseased muscle as compared with control muscle and that primary skeletal muscle cells can secrete inflammatory mediators, directly participating in inflammasome formation. Moreover, diseased muscle cells expressed innate immune molecules, suggesting that affected muscle may directly contribute to inflammation in muscular dystrophy and providing a new therapeutic target for LGMD2B.


muscular dystrophy肌肉萎縮
inflammation 發炎；炎症

Better animal-free test for chemicals that can cause contact dermatitis

ScienceDaily (2010-06-01) -- Scientists are reporting development of a fast, simple, inexpensive method for determining whether chemicals in consumer products and workplaces may cause skin allergies in people -- a method that does not involve use of animals.

不需動物的實驗, 人體皮膚是否會過敏....

現存的化學藥劑檢測使用的物有: glutathione 會類似皮膚蛋白質, 且與致敏物結合.
但科學家稱, 早期的皮膚敏感試驗皆不合適.

本研究的皮膚蛋白質替代物質為nitrobenzenethiol : 與皮膚過敏源比較, 此化合物極合適screen基本的致敏物質.

Journal Reference:
Itai Chipinda, Risikat O. Ajibola, Moshood K. Morakinyo, Tinashe B. Ruwona, Reuben H. Simoyi, Paul D. Siegel. Rapid and Simple Kinetics Screening Assay for Electrophilic Dermal Sensitizers Using Nitrobenzenethiol. Chemical Research in Toxicology, 2010; 23 (5): 918 DOI: 10.1021/tx100003w